There are a number of factors that predispose, cause and worsen pelvic organ prolapse. Not only do genetic factors and race influence the risk of prolapse but loss of support to the pelvic floor can be happen when any part of the pelvic floor is injured.
Injury can occur during vaginal delivery, surgery, pelvic radiation or with pelvic fractures from falls or accidents. In addition, constipation, chronic straining, chronic cough, heavy lifting and obesity are all condition that increase the risk of prolapse. Aging, menopause and loss of estrogen also contribute to weakening of the pelvic floor and development of prolapse.